HORDB

ID: hor001192
Uniprot ID: A8XK40
Protein name: Neuropeptide AF22
Gene name: flp-11
Organism: Caenorhabditis briggsae
Family: FMRFamide related peptide family
Source: animal
Expression: NA
Disease: NA
Comments: NA
Taxonomy: Caenorhabditis (genus), Peloderinae (subfamily), Rhabditidae (family), Rhabditoidea (superfamily), Rhabditomorpha (infraorder), Rhabditina (suborder), Rhabditida (order), Chromadorea (class), Nematoda (phylum), Ecdysozoa, Protostomia, Bilateria, Eumetazoa, Metazoa (kingdom), Opisthokonta, Eukaryota (superkingdom), cellular organisms
GO MF: GO:0071855 neuropeptide receptor binding
GO BP: GO:0007218 neuropeptide signaling pathway; GO:0030431 sleep
GO CC: NA

Sequence: NGAPQPFVRF
Length: 10
Propeptide: MTKFSALVLILVIFVAASFAQPYDDVSAEKRAMRNALVRFGRASGGMRNALVRFGKRSAMDEEDFSPESSLQGKRNGAPQPFVRFGRSGQIDHMHDILSTLQKLQYAGNK
Signal peptide: MTKFSALVLILVIFVAASFA
Modification: NA
Glycosylation: NA
Mutagenesis: NA

Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)

hor001192_AF2.pdb

hor001192_ESM.pdb

Mass:	129299	Formula:	C53H77N15O13
Absent amino acids:	CDEHIKLMSTWY	Common amino acids:	FP
pI:	10.55	Basic residues:	1
Polar residues:	2	Hydrophobic residues:	4
Hydrophobicity:	-35	Boman Index:	-1435
Half-Life:	1.4 hour	Half-Life Yeast:	3 min
Half-Life E.Coli:	>10 hour	Aliphatic Index	39
Instability Index:	6252	Extinction Coefficient cystines:	0
Absorbance 280nm:	0

PubMed ID: 18760316
Title: Comparative Peptidomics of Caenorhabditis Elegans Versus C. Briggsae by LC-MALDI-TOF MS